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149 recruiting studies matching your filters

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Trial of Lepodisiran to Investigate the Effect on Coronary Plaque in Adults With Elevated Lp(a) Who Have Established Atherosclerotic Cardiovascular Disease or Are at Risk for a First Cardiovascular Event

Lipoprotein(a), also known as Lp(a), is a protein that carries cholesterol and proteins in your blood. People with high Lp(a) have a higher risk for heart dise…

AtherosclerosisCardiovascular DiseasesLipoprotein(a)

Estimated

~$10 – $7,500

Eli Lilly and CompanyNCT07613294

Observational

Improving Cardiovascular Health in Veterans With PTSD by Treating Trauma-Related Nightmares With NightWare

The purpose of this study is to learn more about the effectiveness of a prescription wrist-wearable device called NightWare (NW) on improving sleep in Veterans…

Post-traumatic Stress Disorder (PTSD)Cardiovascular DiseasesAutonomic Dysfunction+4 more

Estimated

~$10 – $5,625

VA Office of Research and DevelopmentNCT06419959

Edwards PASCAL Transcatheter Tricuspid Valve Repair System Coverage With Evidence Development Study (The CLASP III TR CED Study)

This Coverage with Evidence Development (CED) study measures the long-term health outcomes of patients with severe, symptomatic Tricuspid Regurgitation who rec…

Tricuspid RegurgitationHeart Valve DiseasesHeart Diseases+2 more

Estimated

~$10 – $1,125

Edwards LifesciencesNCT07859709

Thrombosis and Inflammation in Vessels Initiative (TIVI)

Background: Diseases related to the immune system, blood clots, and blood vessels can affect every part of the body. These diseases are now known to be interr…

Cardiovascular DiseasesVascular Diseases

Estimated

~$10 – $675

National Heart, Lung, and Blood Institute (NHLBI)NCT06552767

Observational

PhillyCEAL: Addressing Disparities in Chronic Disease Self-management Through an Enhanced Community Health Worker Program

Cardiovascular disease (CVD) disproportionately affects racial/ethnic minorities and underserved populations in Philadelphia. This study aims to evaluate the e…

DisparitiesCommunity Health WorkersCardiovascular Diseases+1 more

Estimated

~$10 – $6,250

University of PennsylvaniaNCT06732102

Phase 3

Evaluation of Fibrotic Disease Activity in Cardiopulmonary Disorders Using 18F-Fibroblast Activation Protein Inhibitor (18F-FAPI-74 PET/CT Imaging)

Background: Injury or diseases of the heart and lung can sometimes cause scar tissue (fibrosis) to build up in those organs. Current imaging scans can see thi…

Allogeneic Stem Cell TransplantationLung Allograft TransplantationInterstitial Lung Disease+3 more

Estimated

~$10 – $5,625

National Heart, Lung, and Blood Institute (NHLBI)NCT07613099

Observational

A Randomized Placebo-procedure Controlled Trial of the Multi-Pole Pulmonary Artery Radiofrequency Ablation Enhancor System PULmonary Artery Denervation Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease

The goal of this clinical study is to evaluate the safety and efficacy of percutaneous pulmonary artery denervation with the Multi-Pole Pulmonary Artery Radiof…

Pulmonary HypertensionHeart Failure With Reduced Ejection FractionHypertension+5 more

Estimated

~$10 – $8,750

Pulnovo Medical, Inc.NCT07214376

Diabetes and Heart Disease Risk in Blacks

It is unknown if obesity contributes to the development of heart disease in African American men and women. This study was created to determine whether there …

Cardiovascular DiseasesDiabetesObesity+1 more

Estimated

~$10 – $675

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)NCT00001853

Observational

Strong Teens for Healthy Schools Change Club: A Civic Engagement Approach to Improving Physical Activity and Healthy Eating Environments

Strong Teens for Healthy Schools (STHS) is a school-based, civic engagement program that empowers middle school students to improve their physical activity and…

Cardiovascular DiseasesNutritionPhysical Activity

Estimated

~$10 – $6,250

Texas A&M UniversityNCT05867433

Observational

Atrial Natriuretic Peptide and Regulation of Cardiometabolic Health: A Genotype-Guided Human Physiological Study

Natriuretic Peptides (NP) are hormones produced by the heart, and they have a wide range of favorable metabolic benefits. Lower levels of these hormones are as…

Cardiovascular DiseasesNatriuretic PeptidesCardiometabolic Diseases+4 more

Estimated

~$10 – $6,250

University of Alabama at BirminghamNCT05216042

Phase 3

EASi-PROTKT™ - A Phase III Double-blind, Randomised, Parallel-group Superiority Trial to Evaluate Efficacy and Safety of the Combined Use of Oral Vicadrostat (BI 690517) and Empagliflozin Compared With Placebo and Empagliflozin in Participants With Type 2 Diabetes, Hypertension and Established Cardiovascular Disease

This study is open to adults with type 2 diabetes, high blood pressure, and cardiovascular disease. People can join the study if they have these conditions and…

Diabetes Mellitus, Type 2HypertensionCardiovascular Diseases

Estimated

~$10 – $7,500

Boehringer IngelheimNCT07064473

Observational

Transition to Cardiac Rehabilitation (T2CR) to Address Barriers of Multimorbidity and Frailty

Cardiac rehabilitation (CR) is a secondary prevention program for patients with cardiovascular disease (CVD). It is especially valuable as CVD increasingly occ…

Cardiovascular DiseasesCardiac RehabilitationTransition of Care

Estimated

~$10 – $5,625

VA Office of Research and DevelopmentNCT06244199