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54 recruiting studies matching your filters

Family Members at INcreased-risk for Developing Inflammatory Bowel Disease (FIND-IBD)

First-degree relatives of people with inflammatory bowel disease ("IBD," including Crohn's disease and ulcerative colitis) have an increased risk for developin…

Inflammatory Bowel Disease (IBD)Ulcerative Colitis (UC)IBD-unclassified (IBD-U)+10 more

Estimated

~$10 – $750

Massachusetts General HospitalNCT06655415

Phase 4

A Phase 4 Study Evaluating Moderate to Severely Active Ulcerative Colitis or Crohn's Disease and the Use of Vedolizumab Subcutaneous Within a Community Setting

Ulcerative Colitis (UC) and Crohn's Disease (CD) are long-term conditions in the gut that can cause diarrhea, swelling (inflammation), bleeding from the anus, …

Ulcerative ColitisCrohn's Disease

A Master Protocol for a Phase 3, Multicenter, Open-label, Long-term Extension Study to Evaluate the Long-term Efficacy and Safety of Mirikizumab in Children and Adolescents With Moderate-to-severe Ulcerative Colitis or Crohn's Disease

The main purpose of this study is to evaluate the long-term efficacy of mirikizumab in pediatric participants with ulcerative colitis (UC) or Crohn's disease (…

Ulcerative ColitisUlcerative Colitis ChronicInflammatory Bowel Diseases+1 more

Estimated

~$10 – $7,500

Eli Lilly and CompanyNCT04844606

Phase 3

A Phase 3b Extension Study to Evaluate the Long-term Safety of Vedolizumab Subcutaneous in Pediatric Subjects With Ulcerative Colitis or Crohn's Disease

The main aim of this study is to learn about medical problems (adverse events) if vedolizumab subcutaneously (SC) is given to a child or teenager with UC or CD…

Ulcerative ColitisCrohn's Disease

Estimated

~$10 – $7,500

TakedaNCT06405087

Longitudinal Immunophenotyping of Patients With Inflammatory Bowel Disease

Background: Inflammatory bowel disease (IBD) is a term used to describe disorders that cause long-term inflammation in the digestive tract. Symptoms include s…

Inflammatory Bowel DiseaseCrohn's DiseaseUlcerative Colitis

Estimated

~$10 – $675

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)NCT07619547

Phase 2

A Phase 2, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of 3 Active Dose Regimens of MORF-057 in Adults With Moderately to Severely Active Crohn's Disease (GARNET)

This is a Phase 2, randomized, double-blind, placebo-controlled, multicenter study to evaluate the efficacy and safety of 3 active dose regimens of MORF-057 in…

Inflammatory Bowel DiseasesCrohn's Disease

Estimated

~$10 – $8,750

Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company)NCT06226883

Phase 3

A Phase 3, Multicenter, Randomized Clinical Study to Evaluate Mirikizumab in Pediatric Crohn's Disease

Study participants will be screened during the platform study and randomly assigned to receive mirikizumab or another intervention. The purpose of the mirikizu…

Crohn's Disease

Estimated

~$10 – $7,500

Eli Lilly and CompanyNCT05509777

Phase 1

An Open-Label, Proof of Concept Study of Vorinostat for the Treatment of Moderate-to-Severe Crohn's Disease, Ulcerative Colitis, and Chronic Granulomatous Disease Colitis Patients and Maintenance Therapy With Ustekinumab

Background: Crohn s disease (CD) is an inflammatory bowel disease. It causes inflammation of the gut. Symptoms may include diarrhea, abdominal pain, fatigue, …

Crohn's Disease

Estimated

~$10 – $5,625

National Institute of Allergy and Infectious Diseases (NIAID)NCT03167437

Phase 3

A Phase 3b, Randomized, Multicenter, Controlled Study of Mirikizumab and Placebo or Mirikizumab Concomitantly Administered With Tirzepatide in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

The main purpose of this study is to evaluate the efficacy and safety of mirikizumab and placebo compared with mirikizumab and concomitantly administered tirze…

Crohn's DiseaseObesity or Overweight

Estimated

~$10 – $7,500

Eli Lilly and CompanyNCT06937099

Phase 2

A Phase 2b, Randomized, Placebo-controlled, Double-blind, Dose-ranging Trial to Assess the Efficacy and Safety of Ontunisertib in Patients With Fibrostenosing Crohn's Disease

Many patients with Crohn's disease (CD) develop fibrotic narrowing (strictures) in their bowel, causing obstructive symptoms such as abdominal pain, cramping, …

Fibrostenotic Crohn's Disease

Estimated

~$10 – $8,750

Agomab Spain S.L.U.NCT07683325

Observational

Effectiveness and Efficacy of a Ketogenic or Carnivore (Lion) Diet for Quality Life and Symptom Burden in Individuals With Symptomatic Inflammatory Bowel Disease or Rheumatoid Arthritis: A Randomized Controlled Clinical Trial

This study is a randomized controlled clinical trial evaluating whether two therapeutic dietary approaches - a ketogenic diet and a carnivore (lion) diet - can…

Rheumatoid Arthritis (RA)Crohn's Disease (CD)Ulcerative Colitis (UC)

Estimated

~$10 – $6,250

Fuller Research FoundationNCT07524244

Phase 2

A Phase 2 Platform Basket Study Evaluating Advanced Therapies in Subjects With Moderately to Severely Active Crohn's Disease or Ulcerative Colitis

Crohn's disease (CD) and Ulcerative colitis (UC) are 2 types of inflammatory bowel diseases which cause long-lasting, severe inflammation (redness, swelling) i…

Crohn's DiseaseUlcerative Colitis

Estimated

~$10 – $7,500

AbbVieNCT07697456