University of California, San Francisco
The purpose of this study is to determine whether the structure and function of the human retina can be studied with high resolution in patients with inherited retinal degenerations using the Adaptive Optics Scanning Laser Ophthalmoscope (AOSLO).
Retinal degenerations are a group of inherited diseases that result in progressive death of the vision cells, or photoreceptors. Currently there is no treatment or cure for any of these diseases and they ultimately cause blindness in affected patients. We propose to investigate the structure and function of the human retina in patients with inherited retinal degenerations using the Adaptive Optics Scanning Laser Ophthalmoscope (AOSLO). We will correlate the images of retinal structure produced by the AOSLO with Optical Coherence Tomography (OCT) images of the retina. In addition, we will study…
Inclusion Criteria: * Subjects must speak and understand English * Subjects must have pupils that dilate to at least 6 millimeters diameter. * Subjects must be willing to travel to University of California (UC) Berkeley. * Subjects are financially responsible for their travel to the San Francisco area if they are not San Francisco residents. Exclusion Criteria: * Cataract * Irregular corneal astigmatism (keratoconus) * Prior refractive surgery
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