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Evaluate How Use of an Inferior Border Saw While Making the Inferior Border Osteotomy During Sagittal Ramus Osteotomy Using the Low and Short Medial Osteotomy Modification Technique Affects the Lingual Fracture Pattern of the Mandible

The purpose of this study is to evaluate if use of an inferior border saw while making the inferior border osteotomy is associated with the medial cortex fract…

Mandibular Surgery

Estimated

~$10 – $6,250

University of Alabama at BirminghamNCT07104656

Evaluation, Treatment, and Follow-up of Patients With Lyme Disease

This study is designed to establish a population of patients with Lyme disease for evaluation, treatment and follow-up to learn more about the infection. Pati…

Lyme Disease

Estimated

~$10 – $675

National Institute of Allergy and Infectious Diseases (NIAID)NCT00028080

Phase 2

A Phase II, Randomized, Multicenter, Open-Label Study Evaluating the Efficacy and Safety of the Combination of Inavolisib Plus Enzalutamide Versus Physician's Choice of ARPI or Docetaxel in Patients With Metastatic Castration-Resistant Prostate Cancer

This study will evaluate the efficacy and safety of the combination of inavolisib plus enzalutamide compared with physician's choice of alternative androgen re…

Metastatic Castration-Resistant Prostate Cancer

Estimated

~$10 – $7,500

Hoffmann-La RocheNCT07287150

Screening and Natural History of Patients With Polyostotic Fibrous Dysplasia and the McCune-Albright Syndrome

Polyostotic fibrous dysplasia (PFD) is a sporadic disorder which affects multiple sites in the skeleton. The bone at these sites is rapidly resorbed and replac…

McCune-Albright Syndrome

Estimated

~$10 – $675

National Institute of Dental and Craniofacial Research (NIDCR)NCT00001727

Phase 2

Phase II Study of the Da Vinci Single Port (SP) Robotic System for Abdominal and Pelvic Procedures

This phase II trial test the effectiveness and safety of a single-port robotic device (the da Vinci single port \[SP\]1098) for use in abdominal and pelvic sur…

Disease or Disorder

Estimated

~$10 – $6,250

City of Hope Medical CenterNCT05672368

Phase 2

A Phase 2b, Parallel-Group, Double-Blind, Placebo-Controlled Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight and Without Type 2 Diabetes

The main purpose of this study, performed under the master protocol W8M-MC-CWMM (NCT06143956), is to examine the body weight-lowering efficacy and safety of ma…

OverweightObesity

Estimated

~$10 – $7,500

Eli Lilly and CompanyNCT07589608

Virology, Immunology and Mechanisms of Liver Disease in Patients With Hepatitis C and Other Liver Diseases

The purpose of establishing a biorepository is to provide high quality specimens (serum, plasma, buffy coat and liver tissue) for future researchers who are st…

Non-Alcoholic Steatohepatitis(NASH)Hepatitis CHepatitis B+5 more

Estimated

~$10 – $750

State University of New York at BuffaloNCT03025074

Phase 1

A Two-Part Phase 1, Randomized, Double-Blind, Placebo-Controlled First-in-Human Study to Assess the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of REGN20423 in Adult Healthy Participants and Adult Participants With Atopic Dermatitis

This study will test a study medicine called REGN20423 to see how effective it is in healthy participants (in Part A) and participants with atopic dermatitis (…

Healthy VolunteerAtopic Dermatitis

Estimated

~$10 – $8,750

Regeneron PharmaceuticalsNCT07527923

Observational

Screening & TReatment fOr Perinatal WomeN With PTSD in Substance Use Care SettinGs in Arkansas (STRONG Moms)

The goal of this study is to examine the feasibility and acceptability of providing Written Exposure Therapy (WET), a brief, evidence-based therapy for post-tr…

Written Exposure Therapy

Estimated

~$10 – $6,250

University of ArkansasNCT07759882

Phase 3

A Phase III, Randomized, Open-label Study of Izalontamab Brengitecan (BMS-986507) in Combination With Osimertinib Versus Osimertinib Monotherapy or Osimertinib in Combination With Platinum-based Chemotherapy as First-Line Therapy in Patients With EGFR-Mutant Locally Advanced or Metastatic Non-small Cell Lung Cancer

The purpose of this study is to evaluate izalontamab brengitecan (iza-bren) combined with osimertinib in participants with previously untreated, locally advanc…

Non-Small Cell Lung Cancer

Estimated

~$10 – $7,500

Bristol-Myers SquibbNCT07680790

Phase 2

Phase 2 Platform Trial to Assess the Efficacy and Safety of Long-acting Antibodies as Single Agents and in Combinations for Moderately to Severely Active Ulcerative Colitis

This is a Phase 2, multicenter, proof-of-concept platform study in adult participants with moderately to severely active ulcerative colitis (UC). The primary g…

Ulcerative ColitisInflammatory Bowel DiseasesColitis+1 more

Estimated

~$10 – $8,750

Spyre Therapeutics, Inc.NCT07012395

Observational Prospective Research Study In Monoclonal Gammopathies leadINg to Myeloma (ORIGIN Study)

The goal of this study is to find markers that may help to predict why some patients who have monoclonal gammopathy of unknown significance (MGUS) or smolderin…

Monoclonal Gammopathy of Undetermined SignificanceSmoldering Plasma Cell Myeloma

Estimated

~$10 – $750

M.D. Anderson Cancer CenterNCT02726750