Global Network for Women's and Children's Health Research Maternal Newborn Health Registry
NICHD Global Network for Women's and Children's Health
Summary
The primary purpose of this population-based study is to quantify and understand the trends in pregnancy outcomes in defined low-resource geographic areas over time, in order to provide population-based data on stillbirths, neonatal and maternal mortality.
Description
The purpose of the Global Network for Women's and Children's Health Research is to develop and test feasible, sustainable interventions to improve the outcome of women and children and to develop research capacity in resource-poor settings. Because most of the sites have weak health care systems, unacceptably high rates of maternal and neonatal mortality and lack birth and death registries, they lack precise data on outcomes and measures of care. Information from a vital registry system will allow the Global Network to document maternal and neonatal mortality, design trials to address the majo…
Eligibility
- Age range
- Not specified
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: * Community-level * Appropriate for long-term registry data collection and the conduct of ongoing Global Network research * At least 300 deliveries per year * Participant-level * Pregnant women intending to deliver within study cluster * Women who deliver within the study cluster * Women who reside in the community but are transferred for care at delivery Exclusion Criteria: * Participant-level * Opt out of consent to include data in the study
Interventions
- OtherThere is no intervention associated with the parent MNHR study. For the MNHR COVID sub-study, participants will be asked to provide a blood specimen at or near delivery.
There is no intervention associated with the parent MNHR study For the MNHR COVID sub-study, each woman will be asked to provide a blood specimen of approximately 3-5 cc at or near delivery (at delivery or 14 days after) to be tested for COVID-19 antibodies. The person collecting the specimen will be a trained member of the registry staff. The ZEUS ELISA SARS-CoV-2 IgG Test System will be used and run at each site. RTI International will provide central quality support of the analyses.
Locations (15)
- University of Alabama at BirminghamBirmingham, Alabama
- University of Colorado DenverAurora, Colorado
- Indiana University School of MedicineIndianapolis, Indiana
- Boston UniversityBoston, Massachusetts
- Columbia UniversityNew York, New York
- University of North CarolinaChapel Hill, North Carolina