OncoTherapy Science, Inc.
The purpose of this study is to determine the maximum tolerated dose (MTD) of OTS167 administered via oral capsule (PO) to patients with relapsed/refractory locally advanced or metastatic breast cancer.
Inclusion Criteria: Dose Escalation and Dose Expansion Cohorts Patients must meet all of the following criteria to be eligible for participation in the study: 1. Female patients, ≥ 18 years of age at the time of obtaining informed consent. 2. Patients with a documented (histologically- or cytologically-proven) breast cancer that is locally advanced or metastatic. 3. Patients with a malignancy that is either relapsed/refractory to standard therapy or for which no standard therapy is available. 4. Patients with a malignancy that is currently not amenable to surgical intervention due to either…
Single arm, no competitor