Perception, Sensation, Cognition and Action in Humans
National Eye Institute (NEI)
Summary
Background: When people see and hear, the brain changes signals from the eyes and ears into perceptions and thoughts. No one fully understands how this happens. Researchers want to explore how healthy brains process sights and sounds. Objectives: To explore how people understand what they see and hear when the brain processes sights and sounds. Eligibility: Participants aged 13-65 who have at least 20/40 vision in at least one eye and do not use a hearing aid. Design: Some participants will take tests online anonymously. They will do computer tasks related to colors and behavior. In-person participants will be screened with medical history and physical exam. They will complete questionnaires and vision and hearing tests. Participants will plan how many testing sessions they will have and when. Sessions last 2-5 hours. They may include: * Magnetic Resonance Imaging: Magnets and radio waves to take pictures of the brain. Participants will lie on a table that slides in and out of a tube. They will do a task during the scan. * Magnetoencephalography: Records magnetic field changes from brain activity. Participants will sit or lie down. A cone will be lowered onto their head. They may do a task during the test. * Electromyography: Electrodes attached to the skin will measure the electrical activity of muscles. * Electroencephalogram: Electrodes on the scalp will record brain waves. * Electrocardiography: Electrodes on the chest will record heart electrical activity. * Tests of memory, attention, thinking, vision, and hearing. * Eye Tracking: Cameras will follow participants eye movements. They may wear a cap with infrared cameras in front of their eyes. During the sessions, participants vital signs may be monitored.
Description
Objective: The experiments covered by this protocol aim to uncover basic knowledge about the brain mechanisms that give rise to perception and cognition. The protocol encompasses sub-studies in volunteers ("participants") to uncover behaviors and their physiological basis. The protocol includes only non- or minimally invasive techniques with minimal risk, including psychophysics, functional magnetic resonance imaging (fMRI), magnetoencephalography (MEG), genetic sequencing, and on-line tests using web-based platforms. The overarching goal of the research is to obtain new knowledge in the orga…
Eligibility
- Age range
- 13–65 years
- Sex
- All
- Healthy volunteers
- Yes
* INCLUSION CRITERIA: Inclusion Criteria for In-lab Participants A subject can be included in the in-lab portion of the study if he/she: * is in good general health; * is between 18 and 65 years old; * has visual acuity of 20/40 in at least one eye (corrected with contact lenses is okay); * has no hearing impairment requiring a hearing aid. * is capable of understanding the procedures and requirements of this study; * is willing and able to provide his/her own informed consent. Inclusion Criteria for On-line Participants A subject can be included in the on-line portion of the study if he/…
Locations (2)
- National Eye Institute (NEI)Bethesda, Maryland
- National Institutes of Health Clinical CenterBethesda, Maryland