Vicryl Rapide Versus Nonabsorbable Suture in Repair of Simple Traumatic Extremity and Trunk Lacerations in Adult Patients
University of California, San Francisco
Summary
This will be a prospective, randomized controlled trial assessing noninferiority of Vicryl Rapide compared to nonabsorbable suture. The study will be conducted in the Community Regional Medical Center emergency department (ED). The aim of this study, then, is to prospectively determine if 3-month cosmesis for traumatic laceration repair of trunk/extremity lacerations in adult patients with Vicryl Rapide is noninferior to nonabsorbable suture.
Description
Study flyers will be posted in all doc boxes to ensure all ED personnel is aware of ongoing studies. Initial ED history and physical examination (standard procedure). Provider identifies patient who is felt to require suture closure. Provider will contact study staff that approved to consent patient to consent the patient for the study. After identification of a patient who meets inclusion criteria, the patient will be screened for exclusion criteria by the investigators using a preprinted form on the outside of the study envelope. If the patient has an exclusion criterion, this will be noted…
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Patient 18-years or older * single laceration on trunk or extremity requiring suture closure * laceration length \> 2-cm * wound to be closed with simple interrupted sutures Exclusion Criteria: * High infection potential * Must have one of the following: * puncture wound * -highly contaminated * devitalized tissue requiring sharp debridement * -bite wounds * -\> 24-hours-old * Low likelihood of good cosmesis * Must have one of the following: -dehisced wound from previous wound closure * -wound * -crush wound * -soft tissue def…
Interventions
- DeviceVicryl Rapide absorbable suture
In general, most laceration repair has been done with sutures on the surface of the skin that do not break down and fall off on their own, so after enough days have passed for the laceration to heal properly, the patient needs to return to the ED to have the sutures removed by cutting them off. These sutures are called "nonabsorbable". Some newer sutures have been designed to slowly dissolve on their own and fall out over several days. These are called "absorbable" sutures. You do not normally need to return to the ED for removal as these should slowly dissolve and fall out on their own.
Locations (2)
- Community Regional Medical CenterFresno, California
- Community Regional Trauma and Burn CenterFresno, California