DOSE DETERMINATION TRIAL: The Start/Persist Studies
University of Connecticut
Summary
The proposed research will conduct the first dose-determination trial to find the optimal number of behavioral counseling sessions (dose) needed to achieve and sustain optimal HIV treatment adherence. The results of this study will determine how much intervention is needed for whom and at what cost to guide health policy and implementation of behavioral interventions designed to improve durable viral suppression.
Description
The proposed research will conduct the first ever dose-determination trial of a behavioral intervention to improve engagement in HIV care, antiretroviral therapy (ART) adherence and HIV viral suppression. The trial is designed to inform the implementation of behavioral interventions, including several in CDC's Compendium of Evidence-Based Interventions. Behavioral counseling has the flexibility and reach to overcome numerous challenges to HIV care, including social, emotional, and structural barriers. However, basic questions of how to best implement and scale-up interventions remain unanswere…
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Confirmed HIV positive * Confirmed prescribed antiretroviral therapy * Confirmed non-adherent to anti-retroviral therapy Exclusion Criteria: * Does not have access to a phone * Does not have access to the internet
Interventions
- BehavioralBehavioral Self-Regulation Adherence Counseling
Telephone-delivered counseling to focus on cognitive-behavioral skills to improve HIV treatment adherence.
Locations (2)
- University of ConnecticutStorrs, Connecticut
- University of Connecticut Field SiteAtlanta, Georgia