Genomic Prediction Inc.
This study aims to develop preimplantation genetic testing methods from embryo culture media (cell free). Genetic testing of culture media will be compared to conventional methods based on embryo biopsies.
Consenting patients will receive standard clinical IVF and PGT. Culture media from embryos will be collected for analysis. Collection of media will include laser assisted collapse of the blastocyst on day 5, 6, or 7 in order to release blastocoel fluid into the culture media. Embryos diagnosed as aneuploid or monogenic disorder affected (abnormal embryos) will be donated for additional analysis with patient consent. Results obtained from culture media will not be provided to the patients. The information obtained from cf-PGT will be compared to results obtained from embryo biopsies obtained a…
Inclusion Criteria: * Patients undergoing IVF electing to utilize LifeView testing (PGT) will be offered participation in this study. Exclusion Criteria: * None
Embryo spent culture media, otherwise discarded as per standard of care, is collected once embryos have completed in vitro culture.
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