Effect of Inspiratory Muscle Training on Physiological Function and Clinical Outcomes After Lung Transplant: A Randomized Controlled Trial
Mayo Clinic
Summary
The purpose of this research is to study the effect of training the inspiratory muscles (i.e. the muscle that allow you to breath-in) on exercise capacity, quality of life, and short-term clinical outcomes in patients post lung transplant.
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: \- All patients who undergo single- or double-lung transplant at Mayo Clinic Florida. Exclusion Criteria: * Patients who do not survive the intra-operative period during the transplant surgery. * Patients undergoing retransplantation. * Patients undergoing multiorgan transplantation. * Patients who are not willing to or who are unable to give written informed consent.
Interventions
- DevicePOWERBreathe Plus®
Commercially available pressure-threshold device
- OtherCardiopulmonary rehabilitation post lung transplant
Pulmonary function, lung diffusing capacity for carbon monoxide, inspiratory muscle strength, and diaphragm dimensions will be assessed in each patient. Each patient will also undergo a cardiopulmonary exercise test (CPET), 6 minute walk test, and an inspiratory muscle endurance test
Location
- Mayo Clinic in FloridaJacksonville, Florida