Mayo Clinic
The purpose of this research is to study the effect of training the inspiratory muscles (i.e. the muscle that allow you to breath-in) on exercise capacity, quality of life, and short-term clinical outcomes in patients post lung transplant.
Inclusion Criteria: \- All patients who undergo single- or double-lung transplant at Mayo Clinic Florida. Exclusion Criteria: * Patients who do not survive the intra-operative period during the transplant surgery. * Patients undergoing retransplantation. * Patients undergoing multiorgan transplantation. * Patients who are not willing to or who are unable to give written informed consent.
Commercially available pressure-threshold device
Pulmonary function, lung diffusing capacity for carbon monoxide, inspiratory muscle strength, and diaphragm dimensions will be assessed in each patient. Each patient will also undergo a cardiopulmonary exercise test (CPET), 6 minute walk test, and an inspiratory muscle endurance test
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