Efficacy of Peppermint Oil in a Randomized, Single-Blind, Placebo Controlled Trial in Women With Interstitial Cystitis/Bladder Pain Syndrome
University of Louisville
Summary
The purpose of this study is to assess the use of peppermint oil as a treatment for Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS).
Description
After being informed about the study and potential risks, all participants will complete validated IC/BPS symptom questionnaires for baseline screening. Once participants meet eligibility requirements and give written informed consent they will be randomized in a 1:1 ratio to peppermint oil (200mg TID) or placebo (also TID). Participants will complete validated IC/BPS questionnaires and follow up surveys over 8 weeks.
Eligibility
- Age range
- 18–65 years
- Sex
- Female
- Healthy volunteers
- Yes
Inclusion Criteria: * Women ages 18-65 years old * Diagnosed with IC/BPS for at least one month prior to study enrollment Exclusion Criteria: * Culture proven urinary tract infection within 1 month of randomization * Gross hematuria * Currently pregnant or breastfeeding * Unable to speak and read English * History of allergic reaction to peppermint, coconut or enteric coating * History of malabsorption syndrome * History of gastroparesis * History of gastric bypass surgery * History of gastrointestinal, genitourinary or pelvic cancer in the last 5 years * History of insulin dependent diabet…
Interventions
- DrugPeppermint oil
Enteric coated peppermint oil taken by mouth three times daily for 8 weeks.
- DrugCoconut Oil
Enteric coated coconut oil taken by mouth three times daily for 8 weeks
Location
- Springs Medical CenterLouisville, Kentucky