Technology Enabled Strategies to Promote Treatment Adherence in Liver Transplant
University of Pennsylvania
Summary
Liver transplantation is increasingly performed for older adults with multiple comorbidities. Medication adherence is key to maintaining proper function of the transplanted liver and optimize health; however, adhering to post-transplant treatment is complex. This trial will study how available technology combined with transplant center resources and caregiver support can optimize medication adherence, quality of life, and health outcomes among new liver transplant recipients at 3 centers.
Description
Liver transplant, the only cure for end-stage liver disease, is a costly and limited resource that increases survival. It is increasingly performed among older adults who have a higher burden of comorbidities, medical complexity, and are at risk of non-adherence. In addition, liver transplant recipients must manage complex immunosuppression regimens to maintain graft function. Inadequate immunosuppression adherence is common post-liver transplant and has many adverse consequences including liver graft rejection, graft failure, and re-transplantation. To maintain their health, liver transplant…
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- Yes
Liver Transplant Recipient Inclusion Criteria: * 18 years or older * Within 3 months of liver transplant * English or Spanish-speaking * Home-dwelling\* * Patient or care partner owns a smart phone and is comfortable receiving text messages and/or using the internet on the smart phone. * \*The definition of "home" includes hotel or short-term housing. Patients who are going to a rehabilitation or skilled nursing facility (SNF) immediately after transplant may still be recruited if the site-PI/Co-I determines they are likely to be discharged to home within 3 months post-transplant. Care Partn…
Interventions
- BehavioralTEST Intervention
The TEST intervention will include standard post-transplant care and include additional touchpoints utilizing the Way to Health system. Details on this intervention are included in the study arm description.
Locations (3)
- University of MiamiMiami, Florida
- Northwestern UniversityChicago, Illinois
- University of PennsylvaniaPhiladelphia, Pennsylvania