Effects of Recorded Music on Clinical and Electroencephalography (EEG) Seizure Activity
Johns Hopkins University
Summary
This research is being done to determine if Mozart music and/or age-appropriate music can reduce the frequency of seizures and epileptiform discharges.
Description
Several prospective studies have demonstrated the impact of Mozart's sonata for Two Pianos (K.448) on interictal epileptiform discharges and/or clinical seizure recurrence in children with epilepsy. While the exact mechanisms by which Mozart music has this effect are not yet established, there continues to be growing evidence demonstrating the positive effects on Mozart music upon seizure frequency and epileptiform discharges. Additional studies are needed to further elucidate the effect of Mozart music on epilepsy given the heterogeneity of protocols used in diverse clinical settings, with th…
Eligibility
- Age range
- 4–17 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Children (age: 4 - 17 years old) who stay at Epilepsy Monitoring Units (EMU) up to 7 days may join. Exclusion Criteria: * Non-English Speaking
Interventions
- BehavioralMusic Stimuli
Nine-minute-long Mozart K.448 (1st movement) and instrumental age-appropriate songs will be played via single-use earbuds with 10 minutes wash-out in between music stimuli.
Location
- Johns Hopkins School of MedicineBaltimore, Maryland