Dronabinol for the Treatment of Postoperative Pain After Arthroscopic Surgery: a Pilot Randomized Trial
Northwestern University
Summary
The purpose of the proposed study is to evaluate the efficacy of dronabinol for postoperative pain after arthroscopic surgery of the knee. The investigators hypothesize that dronabinol will relieve pain, reduce opioid consumption and will result in few negative side effects. If this pilot study shows promising results the investigators will expand the trial to include additional arthroscopic surgeries (hip, shoulder) and other types of orthopaedic surgery.
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Age 18 years or older * Patient who will undergo arthroscopic surgery of the knee including, but not limited to, * Meniscectomy * Synovectomy * Chondroplasty * Loose body removal Exclusion Criteria: * Patients under age 18 years * Patients who cannot provide consent * Patients who are pregnant, breast feeding, or are trying to become pregnant during the study period * Patients with an allergy to any of the study drugs * Patient who are lactose-intolerant * Revision surgery * Open surgery * Comorbidities preventing surgery * Patients with a history of mania, de…
Interventions
- DrugDronabinol
5mg 2x daily for 7 days
- DrugPlacebo
1 caplet 2x daily for 7 days
Location
- Northwestern University Feinberg School of MedicineChicago, Illinois