Psorcast Study: A Smartphone-based Study of Psoriasis and Psoriatic Arthritis
Sage Bionetworks
Summary
The purpose of this study is to understand variation in the symptoms of psoriasis and psoriatic arthritis using simple, scalable smartphone-based measurements. This study uses an iPhone app to record these symptoms through questionnaires and sensors.
Description
Psoriatic disease exhibits a spectrum of symptoms and can transition from psoriasis (PsO), largely affecting the skin, to psoriatic arthritis (PsA) involving widespread musculoskeletal inflammation. Early detection of the PsO-to-PsA transition and rapid administration of effective treatment is essential, as a delay in diagnosing PsA by as little as 6 months can lead to irreversible joint damage. This "ticking clock" paradigm drives the need for frequent monitoring and effective therapeutic intervention as early as possible to attenuate or possibly prevent disease progression. Using a suite of…
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: * Adult age 18 and older who consent to participate in the study * Own a compatible iPhone or iPod Touch device running iOS 12.2 or above * Be able to read and understand an official language of the country of participation Exclusion Criteria: * Age 17 years or younger * Not a resident of the a country where the app is approved for use * Not have a personal (i.e., not shared) iPhone (4s or newer running iOS 8.0 or later) * Not be able to read and understand an official language of the country of participation
Interventions
- BehavioralParticipant self-assessment surveys
At enrollment, participants are asked to complete a baseline health history, family history, and a participant-reported symptom inventory.
- BehavioralPsoriasis Draw
Participants are asked to draw the location and size of psoriasis they currently experience. Participants are provided a body template onto which they can draw on their screen. Investigators estimate the percentage of body area affected.
- BehavioralPsoriasis Area Photo
Participants are asked to take a picture of a representative psoriasis plaque and indicate the location of the plaque. They are asked to take a picture of the same area over time. The investigators are developing computer vision algorithms to assess the plaque.
- BehavioralFinger and Toe Photos
Participants are asked to take pictures of the back of each hand and the top of each foot. These photos can be used to assess finger and toe swelling as well as psoriatic nail involvement. The investigators are developing computer vision algorithms to assess psoriatic nail involvement and digit swelling.
- BehavioralDigital Jar Open
Location
- Sage BionetworksSeattle, Washington