Yale University
The purpose of this study is to use non-invasive brain imaging methods (MEG and EEG) to characterize the effects of THC on brain activity during learning.
The goal of this study is to use multimodal MEG/EEG to gain novel insight into the acute effects of THC on neural noise and its interaction with the fast information processing dynamics of the brain's cognition-related functional neural networks.
Inclusion Criteria: * Cannabis use at least once in the past 12 months * No cannabis use during the course of the study confirmed with negative urine toxicology at screening and on each test day * Good physical and mental health Exclusion Criteria: * Cannabis naïve individuals * Lifetime or current medical, psychiatric or psychosocial disorders or history that is deemed unsuitable for participation in the study per PI discretion. * Positive pregnancy test, lactation, or refusal to practice birth control for the duration of the study and for two weeks following completion * Major current or…
Participants will receive THC into a rapidly flowing IV infusion.
Participants will receive an equivalent amount (about 1-2 ml) of placebo (sterile 190 proof USP ethanol). The placebo does not produce any measurable blood alcohol levels or subjective/behavioral effects.
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