Integrated Molecular and Clinical Profiling to Improve Disease Characterization and Outcome Prediction in Nodal Marginal Zone Lymphoma
International Extranodal Lymphoma Study Group (IELSG)
Summary
International retrospective observational cohort study aimed to describe a molecular classification for NMZL.
Description
Already existing and coded tumor biological material and health-related patient data will be retrospectively collected from institutional biobanks and patients' charts or electronic medical records upon receipt of ethical approval. Each patient enrolled in the study will be assigned to a unique identification numerical code upon registration in the study. The unique identification code will be used to record health-related data and to label biological samples. The coded biological material will be transferred to the coordinating center at the Oncology Institute of Southern Switzerland and Inst…
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: 1. Male or female adults 18 years or older 2. Diagnosis of NMZL on lymph node histology after Jan 1st, 2000 3. Availability of tumor material from lymph node (either frozen or FFPE) collected when the patient was treatment naïve 4. Availability of the baseline and follow-up annotations Exclusion Criteria: 1\. Nodal spread of a clinically occult extranodal MZL (this must have been ruled out by carefully evaluating the extranodal tissues draining to the involved lymph nodes by imaging or endoscopy)
Locations (36)
- University of MiamiMiami, Florida
- Weill Cornell MedicalNew York, New York
- Hematology Center after Prof. YeolyanYerevan
- University Hospital Centre ZagrebZagreb
- AO SS Antonio e Biagio e C. ArrigoAlessandria, AL
- Istituto Tumori "Giovanni Paolo II" I.R.C.C.S.Bari, BA