Reducing Persistent Fatigue Following Hematopoietic Stem Cell Transplantation
Massachusetts General Hospital
Summary
The purpose of this study is to assess whether a cognitive-behavioral therapy (CBT) for fatigue intervention is acceptable, feasible, and effective at managing fatigue and improving quality of life for patients following hematopoietic stem cell transplant (HCT).
Description
This research is being done to determine whether a cognitive-behavioral therapy (CBT) for fatigue intervention is feasible and effective at managing fatigue and improving quality of life in patients following hematopoietic stem cell transplant. An open pilot of 6 participants will precede the randomized controlled trial. Study procedures for the open pilot include screening for eligibility, intervention Zoom sessions, questionnaires, and exit interviews with study staff. Patients participating in the subsequent randomized controlled trial will be randomized into one of two study groups: CBT…
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria * adult patients (≥ 18 years) * have the ability to speak and read English * have undergone autologous or allogeneic transplant \> 6 months prior to enrollment * no evidence of disease relapse requiring therapy * no new other malignancy requiring therapy after transplant * report moderate to severe fatigue in the past week (FSI average severity item rating ≥ 4 of 0-10) * are currently receiving their care at the MGH Blood and Marrow Transplant Clinic Exclusion Criteria * Patients with active cognitive impairment or uncontrolled psychiatric illness such as schizophrenia th…
Interventions
- BehavioralCBT for Fatigue
10, individualized counseling sessions with a behavioral health counselor via Zoom platform.
- BehavioralUsual Care
Standard transplant care.
Location
- Massachusetts General Hospital Cancer CenterBoston, Massachusetts