Patient-Tailored Physical Activity Intervention Among Older Women With Gynecologic Cancers Undergoing Chemotherapy (Fit4Treatment)
Northwestern University
Summary
The primary purpose of the study is to determine which of four components (symptom-burden tailored app, exercise partner, oncology provider engagement, coaching) added to a core intervention of a wearable activity tracker and commercially available app, will improve physical activity. The findings will generate meaningful knowledge about how to best increase physical activity in older gynecologic cancer patients receiving systemic cancer therapies to improve quality of life and cancer-specific survival.
Description
Gynecologic cancers include ovarian, uterine and cervical cancers and represent 102,000 cases of cancer in the United States every year; 60% occur in women greater than age 60. Older patients with gynecologic cancers have higher rates of advanced stage at presentation, more aggressive histology and more commonly require adjuvant treatment with systemic therapies such as chemotherapy, immunotherapy or targeted therapies. This chemotherapy, as well as underlying cancer, cause accelerated aging and toxicity, leaving women vulnerable to functional decline, increased frailty, decreased health relat…
Eligibility
- Age range
- 60+ years
- Sex
- Female
- Healthy volunteers
- No
Inclusion Criteria: * Female; \> 60 years of age * Diagnosis of endometrial/uterine, ovarian, cervical or vulvar/vaginal cancer * Undergoing or planning to undergo any systemic treatment for a gynecologic malignancy (e.g., chemotherapy, immunotherapy, anti-angiogenic therapies, targeted therapies, etc.) * Willing to try to identify an exercise partner to participate with them, if needed * Fluent in English Exclusion Criteria: * Uncontrolled cardiovascular disease or other major contraindications to physical activity * Active brain metastases * Cognitive or functional limitations that preclu…
Interventions
- BehavioralFit4Treatment
This study will test the core intervention of an activity tracker and commercially available app (Fitbit) in addition to four components which are expected to improve physical activity. The intervention will be delivered over 12 weeks with a 12 week follow up period.
Location
- Northwestern UniversityChicago, Illinois