Can Food Timing Reduce Your Diabetes Risk?
Brigham and Women's Hospital
Summary
The goal of this clinical trial is to test whether food timing impacts metabolic health in healthy participants. Participants will: * complete 2 inpatient stays * be provided with test meals * have frequent blood draws
Description
The investigators aim to investigate the influence of different food timing, without changing 24-h caloric and nutrient intake, on glucose and fat tolerance and energy expenditure in healthy people on a simulated day or night shift.
Eligibility
- Age range
- 18–45 years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: * Healthy with no acute or chronic medical and psychiatric disorders * BMI: 18.5-29.9 kg/m2 Exclusion Criteria: * Smokers, current tobacco or e-cigarette use * Drug or alcohol dependency * Pregnant
Interventions
- BehavioralDay shift protocol - Diet order A-B
Research participants will be assigned to day shift condition and Diet A-B order condition.
- BehavioralDay shift protocol - Diet order B-A
Research participants will be assigned to day shift condition and Diet B-A order condition.
- BehavioralNight shift protocol - Diet order A-B
Research participants will be assigned to simulated night shift condition and Diet A-B order condition.
- BehavioralNight shift protocol - Diet order B-A
Research participants will be assigned to simulated night shift condition and Diet B-A order condition.
Location
- Brigham and Women's HospitalBoston, Massachusetts