Fundamental Biobehavioral Mechanisms Underlying the Integrated Development of Emotion, Attachment, and Nutritive Intake in the Mother-Infant Dyad
University of Michigan
Summary
The rate of weight gain in the first year of life is risk factor for future obesity. The study will test (1) a model of l mechanisms underlying the development of emotion, attachment, and nutritive intake; and (2) the association with maternal feeding behavior, child eating behavior, dietary intake, and adiposity.
Description
This multi-year study was originally accurately registered as an observational study. The outcome measures are not measuring dependent variables based on the interventions; rather the interventions are experiments to categorize infant responses for the purpose of grouping infants according to their behaviors. There are small trials associated with the grant at National Clinical Trial numbers (NCT #s): NCT06072664, NCT06072651, and NCT06072638 to analyze behaviors at 18 and 36 months of age. However, because the NIH grant covering this study needs to be linked to a trial for computer smart logi…
Eligibility
- Age range
- 0+ years
- Sex
- All
- Healthy volunteers
- Yes
To be eligible to participate in this study, they mother-child dyad must meet all of the following criteria: 1. Provision of signed and dated informed consent form by mother for herself and infant 2. Stated willingness by mother to comply with all study procedures and availability for the duration of the study 3. Infant gestational age 37.0 - 42.0 weeks based on maternal report of due date and child's birth date 4. Infant birth weight by maternal report appropriate (≥ 3rd percentile and ≤ 97th percentile) for gestational age and sex based on US Natality Data set. 5. Mother is biological mothe…
Interventions
- BehavioralBonding-Evoked Oxytocin
Mother participates in bonding activity with infant at ages 1, 3, and 6 months
- BehavioralDistress Relieving Effects of Sucrose
Researcher elicits distress in the infant (sequence of unswaddling, pacifier removal, and arm restraint), followed by delivery of oral sucrose in one condition and water in other condition
- BehavioralHedonic Response to Sucrose
Researcher gives infant opportunity to suck from two bottles, one containing sucrose and one plain water at infant ages 1, 3, and 6 months
- BehavioralTypical versus Challenging Feeding-Social
Mother feeds infant on four counterbalanced days at infant ages 1, 3, and 6 months crossing two conditions: (1) regular size nipple versus smaller aperture nipple ('challenging') and (2) providing social interaction while feeding versus not.
- BehavioralCaloric Compensation-Social
Mother feeds infant on four counterbalanced days at infant ages 1, 3, and 6 months crossing two conditions: (1) offering a bottle feeding ad lib for 3 hours versus offering a bottle feeding every hour for 3 hours; (2) providing social interaction while feeding versus not.
Location
- University of MichiganAnn Arbor, Michigan