Achieving Understanding of the Natural History of Sickle Cell Trait (AUNT)
National Alliance for Sickle Cell Centers
Summary
The main purpose of this study is to create a longitudinal cohort of those with Sickle Cell Trait (SCT) to better understand the hematologic phenotype for those that carry HbS, assess for differences in those with varying quantities of HbS and assess for potential clinical complications of SCT.
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: 1. Are willing to voluntarily participate and sign the study consent 2. Know/suspect they have SCT and are willing to get tested to confirm/learn about their SCT status 3. Adults ages 18 and older Exclusion Criteria: 1. Unwilling to sign consent 2. Known end-stage renal disease or dialysis 3. Known SCD (including sickle cell-beta thalassemia) 4. People who do not have SCT
Interventions
- OtherBiologic Specimen Collection
Participants will have blood and urine collected at Baseline
Locations (10)
- University of AlabamaBirmingham, Alabama
- Loma Linda University Health CareLoma Linda, California
- Nemours Children's HospitalWilmington, Delaware
- Indiana UniversityIndianapolis, Indiana
- Functional FluidicsDetroit, Michigan
- University of North CarolinaChapel Hill, North Carolina