University of Colorado, Denver
The purpose of this study is to assess the effectiveness of prophylactic oxytocin on hemorrhage rates for second trimester dilation and evacuation (D\&E) in the clinic setting.
Inclusion Criteria: * clinic-based D\&E at 18 weeks gestational age and above * speaks English or Spanish Exclusion Criteria: * refuses IV * history of coagulopathy * anticoagulant use in the preceding five days * chorioamnionitis or sepsis * suspected placenta accreta spectrum * intrauterine fetal demise * multiple gestation * use of misoprostol for cervical preparation
40 units IV oxytocin once in a 1000 mL bag of normal saline
1000 mL bag of normal saline alone