Control of Incomplete Spinal Cord Injury-Related Spasticity by Means of Vibrotactile Coordinated Reset Fingertip Stimulation
Stanford University
Summary
The purpose of our study is to evaluate vibrotactile Coordinated Reset (vCR) and its effects on spasticity symptoms in incomplete spinal cord injured patients. vCR will be administered with a device called the Stanford CR Glove. vCR is expected to provide patients with a non-invasive alternative to the most widely used treatments such as oral baclofen and or deep brain stimulation. Patients will be followed for three months and will be asked to come to the lab for clinical testing 4 times during this period. A total of 30 patients will be included in the study.
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: 1. Age at the time of enrollment: Any adult ages 18 and over 2. Spinal Cord Injury: ASIA C or D injury at level C1-T1 3. Duration of incomplete spinal cord injury minimum 1 years clinical/fundamental 4. Spasticity with a of MAS score \>3 present in upper extremities. 5. Fluent in English 6. If patient is on medication that affects brain function or alters EEG activity, the patient must feel comfortable going off this medication prior to EEG recording. 7. Appropriate social support if required during an off-medication state. 8. Comfortable with technology; can use a compute…
Interventions
- DeviceVibrotactile Coordinated Reset
The experimental device, the Stanford CR Glove, is designed to deliver vibratory stimulation to the fingertips of each hand according to a specific pattern, known as vibrotactile Coordinated Reset, which theoretically disrupts abnormal neuronal synchrony and is expected to restore function.
Location
- Stanford UniversityStanford, California