MedSupport: A Novel Multilevel Intervention to Identify and Address Barriers to Pediatric Medication Adherence

Summary

This clinical trial identifies and addresses barriers to pediatric medication adherence among families of children with acute lymphoblastic leukemia. Pediatric nonadherence (noncompliance) to medication is a significant public health problem, and rigorous research repeatedly documents that nonadherence increases risk for hospitalization, healthcare cost, disease progression, and death. Pediatric acute lymphoblastic leukemia (ALL) patients who miss 5% of 6-mercaptopurine (6-MP) doses within the 2-year 6-MP regimen have a 2.7-fold risk of cancer that comes back after a period of improvement (relapse). To address these families' needs, researchers have developed MedSupport, a theory-based multilevel intervention with targets at the organizational, healthcare team, and caregiver levels that is designed to address root barriers to medication adherence. This study is being done to better understand families' experiences giving their child oral chemotherapy at home and to help families cope with the day-to-day challenges of giving their child medication.

Description

Eligibility

Age range

Not specified

Sex

All

Healthy volunteers

Yes

Interventions

• Other
  Best Practice

  Receive usual care

• Procedure
  Biospecimen Collection

  Undergo blood sample collection

• Other
  Electronic Health Record Review

  Ancillary studies

• Other
  Interview

  Ancillary studies

• Other
  Medical Device Usage and Evaluation

  Receive MedSupport intervention

• Other
  Medical Device Usage and Evaluation

  Use MEMS device

• Other
  Survey Administration

Location