Improving Oral Chemotherapy Adherence in Maintenance for Adolescents and Adults With Acute Lymphoblastic Leukemia Using Text Messages
University of Chicago
Summary
The purpose of this section is to learn how text message reminders might help with regularly taking chemotherapy medications for Adolescents and Adults with Acute Lymphoblastic leukemia (ALL).
Description
This study aims to compare adherence to oral mercaptopurine and methotrexate during the first 84-day cycle of maintenance therapy for adolescent and young adult patients with Acute Lymphoblastic Leukemia on pediatric-based regimens between those who receive the high intensity text message intervention and those who receive standard-of-care. It is believed that high-intensity text messages will increase patient adherence within cycle 1.
Eligibility
- Age range
- 15–39 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Age of 15-39 years-old at the time of initial ALL diagnosis * Diagnosed with ALL * Currently receiving treatment with pediatric-based regimen that includes maintenance with mercaptopurine and methotrexate (e.g., CALGB 10403). Study participation begins with the start of maintenance, so enrollment occurs prior to the start of maintenance. Exclusion Criteria: * Patient or caregiver who would receive text message reminders does not have a cell phone that receives text messages * Patient does not wish to participate * Text messages will be crafted in the patient's preferre…
Interventions
- OtherHigh Intensity
Daily texts
- OtherNo Text Messagings
Standard Care
- OtherLow Intensity Text Messaging
Weekly Texts
Location
- University of Chicago Medicine Comprehensive Cancer CenterChicago, Illinois