A Randomized, Placebo-controlled, Multicenter, Study to Evaluate the Impact of Upadacitinib on Spondyloarthritis Outcomes in Patients With Active Psoriatic Arthritis (UP-SPOUT)
CARE ARTHRITIS LTD.
Summary
A Randomized, Placebo-controlled, Multicenter, Study to Evaluate the Impact of Upadacitinib on Spondyloarthritis Outcomes in Patients with Active Psoriatic Arthritis (UP-SPOUT)
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: 1. Subject ≥18 of age at the screening visit. 2. Subject must be able to understand and willing to adhere to all protocol requirements and voluntarily sign and date an informed consent, approved by an Independent Ethics Committee (IEC)/institutional review board (IRB), prior to the initiation of any screening or study-specific procedures. 3. Diagnosis of PsA by their treating rheumatologist. 4. Classification of PsA according to the CASPAR criteria19: Inflammatory articular disease (joint, spine, or entheseal) AND at least 3 points of the following categories: a) Evide…
Interventions
- DrugUpadacitinib 15 MG [Rinvoq]
15mg tablet once per day.
- DrugPlacebo
15mg tablet once per day.
Locations (5)
- University Hospitals Cleveland Medical CenterCleveland, Ohio
- Oregon Health and Science UniversityPortland, Oregon
- University of PennsylvaniaPhiladelphia, Pennsylvania
- The Ottawa Hospital Research InstituteOttawa, Ontario
- Groupe de Recherche en Maladies Osseuses (G.R.M.O.) Inc.Québec, Quebec