The Effect of Lower Extremity Eccentric Resistance Training on Fatigue in Multiple Sclerosis
Hunter College of City University of New York
Summary
The goal of this observational study is to compare the impact of eccentric resistance training to traditional resistance training on fatigue in persons with multiple sclerosis (MS). The primary question this study is asking is the following: is eccentric resistance training more fatiguing than traditional resistance training in persons with MS?. Participants will be asked to come for two sessions for two weeks. In the first week, subjects will undergo a bout of either traditional or eccentric resistance training. The next day they will return to assess their level of fatigue. The following week the subject will return and undergo whatever type of training they did not experience the first week, and it's effects on fatigue will again be assessed. The difference between the subjects level of fatigue for either condition will be compared.
Description
Persons with multiple sclerosis (MS) have mobility deficits. Exercise is commonly used to treat these mobility deficits, but must be done so judiciously in order to limit the effects of fatigue, one of the most common disease findings. In persons with MS ,fatigue can limit the amount of exercise performed. Eccentric training, where a muscle is lengthened under resistance has been shown to produce greater gains in strength with less energy expenditure when compared to traditional strength training where a muscle is both lengthened and shortened under resistance. However, eccentric strength trai…
Eligibility
- Age range
- 18–75 years
- Sex
- All
- Healthy volunteers
- Not specified
Inclusion Criteria: * Definitive diagnosis of Multiple Sclerosis. * Ability to walk for 6 minutes continuously with or without assistive device * Ability read, understand and sign and informed consent Exclusion Criteria: * Evidence of recent exacerbation in the last 2 months prior to starting the study * Orthopedic, cardiopulmonary, or non -MS neurologic condition that could interfere with carrying out the study protocol
Interventions
- BehavioralResistance training
Eccentric resistance training and tradional resistance training
Location
- Hunter College, Physical Therapy Department, City University of New YorkNew York, New York