A Cohort Study of Older Adults From Under-resourced/Under-represented Communities Diagnosed With Subjective Cognitive Decline (SCD) or Mild Cognitive Disorder (MCI) Through Standard of Care Tele-Cog Visits (Tele-Cog)
Ohio State University
Summary
Overall, this study's primary aim is to establish a prospective, longitudinal, observational cohort study of older adults at risk for dementia from under-resourced/underrepresented communities. More specifically, older adults diagnosed with subjective cognitive decline (SCD) or Mild Cognitive Impairment (MCI) during clinical care offered via the Tele-Cog clinic would be recruited for more comprehensive data collection to characterize the clinical presentation and course of illness over multiple timepoints spread out longitudinally.
Description
Clinical data obtained as part of standard of care will be collected from the medical record (including clinical diagnosis, cognitive and other neuropsychological test scores, lab results, neuroimaging data, etc.) and additional data (neuropsychological test batteries and clinical questionnaires if not already obtained) would be obtained at research study visits. Participants will be asked to participate in annual research visits for up to 5 years.
Eligibility
- Age range
- 50+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: 1. Adults ages 50 years and older 2. Diagnosed with subjective cognitive concerns (SCD) or objective cognitive decline with mostly intact functioning (MCI diagnosis) as part of clinical work up 3. Fluent in English 4. Able to provide voluntary informed consent 5. Willing and able to undergo all study procedures 6. Able to delegate, if possible, a study partner to contribute information regarding daily activities and cognition Exclusion Criteria: 1. Diagnosis of dementia at baseline. 2. Inability to give informed consent. 3. High risk of adverse emotional or behavioral re…
Interventions
- BehavioralAssessments
Participants will undergo a standard battery of neuropsychological measures, behavioral questionnaire, and functional assessment to monitor cognition and function over time. Clinical data obtained as part of standard of care will be collected from the medical record
- OtherNeuroimaging volumetric measures
Neuroimaging volumetric measures will be obtained from already conducted standard of care neuroimaging.
- OtherBiofluid samples
Biofluid sampling data will be obtained through another protocol. All participants will be required to sign that consent to participate in this trial.
Location
- The Ohio State UniversityColumbus, Ohio