Balance Control and Recovery in Diabetes Peripheral Neuropathy
Lisa Griffin
Summary
In this study the effects of diabetic peripheral neuropathy will be assessed on balance control, balance recovery, and muscle electrical activity in adults over 50 years. Aim 1: Determine muscle activity and balance control during a sit-to-stand in adults age above 50 with and without diabetic peripheral neuropathy. Aim 2: Assess local balance recovery and latency responses to lateral surface perturbation during quiet standing.
Description
Diabetic peripheral neuropathy (DPN) is a common condition affecting patients with diabetes. The prevalence of DPN increases with age and the duration of having diabetes. Approximately 30% of patients with diabetes have peripheral neuropathy globally, and 4.5 million Americans have DPN. DPN typically affects more distal peripheral nerve branches, resulting in sensory loss. DPN causes axonal damage and leads to a loss of muscle strength. These degenerative effects significantly contribute to fall risks and feelings of instability. Falls most commonly occur during transitional tasks such as th…
Eligibility
- Age range
- 50–99 years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: * Type II diabetes with peripheral neuropathy Exclusion Criteria: * Foot ulcer * Partial amputation * Have experience of Stroke * Painful neuropathy * Inability to stand or walk independently
Interventions
- Behavioralsit-to-stand
test for balance during movement from sitting to standing
- Behavioralstand to sit
test for balance during movement from standing to sitting
- Behavioralstanding perturbation
test for balance recovery following perturbation
- OtherMRI of sciatic nerve
measure of peripheral nerve diameter
Location
- The University of Texas at AustinAustin, Texas