Physiologic Effects of Nasal High Flow on Exercise Tolerance in Chronic Obstructive Pulmonary Disease (COPD)
University of Miami
Summary
This study aims to assess whether to describe the effects of the administration of nasal high flow (NHF) at 70 liters per minute (L/min) in a 6-Minute Walk Test (6-MWT) among Chronic Obstructive Pulmonary Disease (COPD) patients and to characterize the association between self-reported dyspnea with and without NHF at 70 L/min following a 6-MWT.
Eligibility
- Age range
- 18–100 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Able to consent * Age 18 years or older * Diagnosis of COPD * Ability to ambulate without assistance * Use of low-flow nasal cannula ≤ 4 L/min or no supplemental oxygen (O2) at all Exclusion Criteria: * Pregnancy * Being on bedrest * Inability to consent or cooperate with the study * Using of \> 4 L/min of supplemental O2 or requiring non-invasive ventilation during the daytime * Hemodynamic instability (resting heart rate \> 130/minute, systolic blood pressure of ≤ 90 mmHg or ≥ 180 mmHg) * Metal implants in the thoracic regions (pacemakers, Automatic Implantable Cardi…
Interventions
- DeviceNasal High Flow Cannula
High flow nasal cannula is a device that provides heated and humidified high flow gases. In-person. Depending on participant's availability, up to 6 times
- DeviceNasal Low Flow Cannula
Low flow nasal cannula is a device that provides low flow gases. In-person. Depending on participant's availability, up to 6 times
Location
- University of MiamiMiami, Florida