A Prospective, Placebo-controlled, Double-blinded, Randomized Clinical Trial Evaluating the Efficacy and Tolerability of Pre and Post Care Skincare Regimen Paired With 1927nm Diode Fractional Laser for Photodamage on the Face
Goldman, Butterwick, Fitzpatrick and Groff
Summary
Compare the effectiveness of laser treatment using CE Ferulic versus vehicle pre/post laser.
Description
Evaluate the efficacy and tolerability of a Skinceuticals CE Ferulic® when used once daily over the course of 14 weeks with 2-week pre-treatment period and 12-week treatment period in pairing with two pre-elected laser treatments with 1927nm non-ablative fractional diode laser treatment for improving skin photoaging signs on the face.
Eligibility
- Age range
- 30–70 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Adult males and females aged 30-70 years (Fitzpatrick I-IV 30-65 years, Fitzpatrick V-VI 30-70 years) * Fitzpatrick skin types I-VI * Subjects in good general health based on investigator's judgment and medical history * Must be willing to give and sign an informed consent form and photographic release form * Must be willing to have examinations of face and digital photographs performed of the face * Physician evaluator classifying the subject as mild to moderate (Score 3-6) on the modified Griffiths 10-Point Scale for the face. * The subject must be planning to undergo…
Interventions
- DrugCE Ferulic
CE Ferulic serum regimen combined with laser treatment
- DrugSham Comparator
Vehicle serum regimen combined with laser treatment
- Device1927nm (Clear and Brilliant Perméa®)
non-ablative fractional diode laser
Location
- West Dermatology Research CenterSan Diego, California