A Randomized, Double-blind Study Comparing the Effects of Three Distinct High Intensity Locomotor Training Protocols on Locomotor Outcomes in Subacute Stroke Patients Undergoing Adult Inpatient Rehabilitation.
NYU Langone Health
Summary
The purpose of this study is to elucidate optimal dosing for High Intensity Gait Training (HIGT) to reduce locomotor disability for those undergoing inpatient rehabilitation (IR) in the subacute phase of stroke recovery. This is a randomized controlled trial conducted at a single IR facility. Investigators will randomize patients to receive one of two distinct HIGT interventions or a high step count intervention during standard care.
Eligibility
- Age range
- 18–95 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: • Primary diagnosis of stroke Exclusion Criteria: * Weightbearing restrictions, uncontrolled cardiopulmonary, metabolic, infectious, or psychiatric disorders, which would preclude aerobic locomotor training * Estimated length of stay of less than 14 days * Non-ambulatory status prior to admission (unable to walk \>50 meters) * Pregnant
Interventions
- BehavioralModerate-Intensity Locomotor Training Program
The moderate-intensity program prescribes participants to exert 50-59% of their heart rate (HR) reserve, or a score of 13-15 on Borg's rating of perceived exertion (RPE) scale.
- BehavioralHigh-Intensity Locomotor Training Program
The high-intensity program prescribes participants to exert at least 60% of their heart rate (HR) reserve, or a score of 16-18 on the RPE scale.
- BehavioralHigh-Step Count Locomotor Training Program
The high step count program prescribes at least 600 steps per session, at less than 50% or HR reserve, or less than 13 RPE.
Location
- NYU Langone HealthNew York, New York