CGM Dynamic Index (CDI) for Predicting Prediabetes in People With Cystic Fibrosis
Indiana University
Summary
The primary objective of this pilot study is to develop a CGM-based model to predict the progression from prediabetes to diabetes in individuals with cystic fibrosis.
Eligibility
- Age range
- 12–55 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * CF individuals aged 12-55 years. * CF without diabetes or with prediabetes (as defined by OGTT and HbA1c). * Willing to use a continuous glucose monitoring system with compatible smart phone for glucose data collection. A person with CFRD and already using CGM, we will just collect their personal CGM data, and they are not required to have OGTT or HbA1c visit. Exclusion Criteria: * Pregnancy. * History of transplant. * Use of immunosuppressant drugs. * Use of oral steroids or any medication known to interfere with glucose. * Allergy to adhesives. * Individuals with se…
Interventions
- DeviceCGM Dynamic Index (CDI)
Participants will undergo one-time oral glucose tolerance test (OGTT) and a one-time use of a CGM device, which will be worn for up to 10 days.
Location
- Indiana University Health, University HospitalIndianapolis, Indiana