Stanford University
This study investigates the time course of change in calcium in the blood after a pregnant subject takes an oral dose of calcium carbonate (commonly marketed as "Tums"). This information is important for trials investigating whether calcium can reduce postpartum hemorrhage, bleeding after delivery.
Inclusion Criteria: * Pregnant female subjects at the study institution, admitted for labor (spontaneous, augmented, or induced) Exclusion Criteria: 1. severe range blood pressure (BP \>160/\>110) within the 48 hours prior to delivery 2. patient age \<18 years or \>45 years 3. renal dysfunction with a documented serum Cr \> 1.0 mg/dL 4. known history of congenital or acquired cardiac disease or history of arrhythmia 5. patient taking digoxin 6. patient currently taking a calcium channel blocker 7. Weight \<55kg or \>100kg, or 8. receiving magnesium infusion within 24 hours prior to or durin…
All participants receive a single, open-label dose of oral calcium carbonate 3000mg
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