Multicenter Symphony IL-6 Monitoring Sepsis ICU Validation Study
Bluejay Diagnostics, Inc.
Summary
The primary objective of this study is to validate a pre-defined IL-6 concentration cutoff that predicts 28-day mortality in patients who are admitted or are intended to be admitted to the ICU diagnosed with sepsis or septic shock.
Eligibility
- Age range
- 22+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Adult patients (≥22 years of age) * Diagnosis of sepsis or septic shock based on: the Third International Consensus Definitions (Sepsis-3 criteria) defined as at least one of the following criteria as determined by a treating physician or study physician investigator. * Sepsis: suspected or documented infection (i.e., use or intent to use antibiotics as an indicator) and organ dysfunction defined by a Sequential Organ Failure Assessment (SOFA) score ≥2 * Septic shock: sepsis requiring vasopressors and serum lactate levels \>2 mmol/L (18 mg/dL) * Admitted or intended…
Locations (5)
- University of Florida College of MedicineGainesville, Florida
- Beth Israel Deaconess Medical CenterBoston, Massachusetts
- Wake Forest School of MedicineWinston-Salem, North Carolina
- Vanderbilt University Medical CenterNashville, Tennessee
- Intermountain HealthSalt Lake City, Utah