A Pilot Study to Investigate the Effects of Combining a Modified Atkins Diet With a Physical Fitness Regimen in Patients Diagnosed With Malignant Glioma
NYU Langone Health
Summary
This is a pilot study assessing the effects of combining a modified Atkins diet with a physical fitness regimen in patients with malignant glioma. A sample size of 15 participants will be enrolled in a 15-week program consisting of two weekly supervised exercise sessions combined with an individualized home exercise program and a modified Atkins diet.
Eligibility
- Age range
- 18–100 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Tissue confirmed diagnosis of high-grade glioma (World Health Organization grade III or IV) * Karnofsky Performance Status (KPS) ≥ 70% * Willing to follow the study intervention and follow-up * Able to give full informed consent Exclusion Criteria: * Currently undergoing initial concurrent radiation/chemotherapy * Severe medical co-morbidities * Any medical condition which prohibits moderate to vigorous physical activity (60-85% HRmax) * Any medical condition which prohibits a restrictive diet * Neurological deficit preventing participation in moderate to vigorous phys…
Interventions
- BehavioralModified Atkins Diet
The Atkins diet is a low-carb eating plan that focuses on balancing protein, fat, and carbohydrates.
- BehavioralFitness Program
12 weeks of two weekly supervised exercise sessions combined with an individualized home exercise program based on physical capabilities and available equipment.
Location
- NYU Langone HealthNew York, New York