Simethicone as Part of an Enhanced Recovery After Surgery (ERAS) Protocol
Madigan Army Medical Center
Summary
By conducting this study, we hope to assess if simethicone (also known as Gas Relief or GasX) has an effect on improving gas pain and bloating specifically in patients undergoing foregut procedures to include bariatric procedures (sleeve gastrectomy, Roux-en-Y gastric bypass), hiatal hernia, and gastric surgery. The purpose of this research is to gather information on the safety and effectiveness of simethicone. Simethicone (more commonly known as Gas Relief or Gas-X) relieves pressure, bloating, and fullness commonly referred to as gas. It is FDA approved. The use of this medication in this research study is consistent with labeling indications.
Description
Patient enrollment Prospective participants will be screened prior to their preoperative appointment based on their presenting complaint (diagnosis) and the indicated surgical procedure (foregut operations). Patients will undergo informed consent by a member of the research team. Patients will complete baseline survey (PROMIS Scale v1.1 - Gastrointestinal Gas and Bloating 13). This is a paper survey that will be provided to them by a member of the research team. Patient randomization Patients will be randomized into simethicone vs placebo groups via unrestricted randomization The research ph…
Eligibility
- Age range
- 18–89 years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: * Foregut procedures Exclusion Criteria: * Non-foregut procedures * Allergy to simethicone * Pregnancy or breastfeeding * Minors under 18 years of age
Interventions
- DrugSimethicone 80 MG
Patients will receive simethicone 80mg four times per day for 2 weeks post-operatively.
- DrugPlacebo
Patients in the control group will receive a placebo pill four times per day for 2 weeks
Location
- Madigan Army Medical CenterTacoma, Washington