A Phase 4, Prospective, Open-Label, Single-Arm Study to Assess the Effectiveness of Tirzepatide After Initiation of Ixekizumab in Adult Participants With Active Psoriatic Arthritis and Overweight or Obesity in Clinical Practice.
Eli Lilly and Company
Summary
The main purpose of this study is to assess the effectiveness of adding tirzepatide to ixekizumab therapy in standard clinical practice in participants with moderate-to-severe PsA and obesity or overweight with at least 1 weight-related comorbidity. The study will last up to 12 months.
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Have a diagnosis of active psoriatic arthritis (PsA) as defined by a rheumatologist or other healthcare professional (HCP) experienced in treating PsA. * Body Mass Index (BMI) of 30 kilograms per meter squared (kg/m²) or greater (obesity) or 27 kg/m2 to \<30 kg/m² (overweight) in the presence of at least 1 weight-related comorbid condition (hypertension, dyslipidemia, type 2 diabetes, obstructive sleep apnea, or cardiovascular disease). * Who have been treated with ixekizumab for approximately 3 months (±1 month) prior to decision to add tirzepatide. * Must be able to in…
Interventions
- DrugTirzepatide
Administered SC
Locations (55)
- AARA Clinical Research - Arizona Arthritis & Rheumatology Associates - AvondaleAvondale, Arizona
- AARA Clinical Research - Arizona Arthritis & Rheumatology Associates - ChandlerChandler, Arizona
- AARA Clinical Research - Arizona Arthritis & Rheumatology Associates - FlagstaffFlagstaff, Arizona
- AARA Clinical Research - Arizona Arthritis & Rheumatology Associates - GilbertGilbert, Arizona
- AARA Clinical Research - Arizona Arthritis & Rheumatology Associates - GlendaleGlendale, Arizona
- AARA Clinical Research - Arizona Arthritis & Rheumatology Associates - MesaMesa, Arizona