Purdue University
The importance of the gut microbiota for general health has been recently elucidated, but little is known about the impact of different types of nutrients on the gut microbiota. The soluble fiber in cereal by-products, arabinoxylan (AX), is known to be beneficial for generally promoting gut health. However, it is unclear whether consuming rice bran (RB), the source of AX, is equally helpful or better than consuming the extracted form of AX. This study aims to reveal the potential benefit of insoluble cereal bran fiber ingredients by comparing the effect of soluble arabinoxylan fiber alone and the mostly insoluble rice bran fiber, containing arabinoxylan, on intestinal health and gut microbiota. A placebo (maltodextrin) will be used as a control, with no significant changes expected in this group for the evaluated outcomes. Participants will: * Consume two different fiber supplements (soluble arabinoxylan or stabilized rice bran) as well as a placebo (maltodextrin) for 3 weeks each, separated by a 2-week washout period. * Provide blood and stool samples at six different time points. * Complete a food and gastrointestinal symptom diary during the intervention periods.
Background: This randomized, crossover clinical trial aims to evaluate the effects of two types of dietary fibers (soluble arabinoxylan and rice bran) compared to a control (maltodextrin) on gut microbiota and intestinal health in healthy adults aged 18-45. Insoluble rice bran, a fiber derived as a cereal by-product, may provide special support of a group of beneficial gut bacteria, and may compare well to its soluble arabinoxylan counterpart. This study will provide insights into whether rice bran, as a fiber source, offers additional benefits compared to the extracted soluble form alone. S…
Inclusion Criteria: * Men or women. * Aged between 18-45 years. * Body mass index between 18.5 and 25 kg/m². * Able to read/speak English. Exclusion Criteria: * Gastrointestinal disorders (inflammatory bowel disease, irritable bowel syndrome, gluten sensitivity/intolerance, etc.). * Those who took antibiotics 3 months before the study. * Individuals taking regular medication or supplements that might affect the gut microbiota. * Individuals undertaking weight-loss diets. * Unstable body weight (±3 kg in the past 3 months), and individuals below 110 lb. * Heavy drinkers (for men, consuming m…
10 grams of soluble arabinoxylan diluted in 200 mL of water, twice daily for 3 consecutive weeks.
10 grams of rice bran fiber diluted in 200 mL of water, twice daily for 3 consecutive weeks.
10 grams of maltodextrin diluted in 200 mL of water, twice daily for 3 consecutive weeks.
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