A Phase 1, Multicenter, Open-Label, Dose Escalation, Dose Expansion and Dose Confirmation Study of BHV-1530 in Adult Patients With Advanced or Metastatic Solid Tumors
Biohaven Therapeutics Ltd.
Summary
This is a Phase 1, first in human (FIH), open-label, multicenter study of BHV-1530 in adult participants with advanced or metastatic solid tumors.
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: 1. Signed, written Independent Ethics Committee (IEC)/Institutional Review Board (IRB)-approved informed consent 2. Age greater than or equal to 18 years 3. Participants consent to provide tumor tissue collected prior to study treatment, preferably from a biopsy performed after their last anticancer therapy and within 90 days of the start of study treatment. An older archival sample may be acceptable with Sponsor approval. 4. Participants must have progressed following, are intolerant of, or have no available standard-of-care therapy. 5. Patients with histologically or cyt…
Interventions
- DrugBHV-1530
BHV-1530 will be administered as an IV infusion on Day 1 of each 21-day cycle
Locations (12)
- Site-107Denver, Colorado
- Site-108Lake Mary, Florida
- Site-110Detroit, Michigan
- Site-115Durham, North Carolina
- Site-112Myrtle Beach, South Carolina
- Site-116Nashville, Tennessee