The GAIN Study: The Gastroschisis And Early Infant Nutrition Study
University of California, Davis
Summary
This study aims to evaluate the feasibility of initiating early feeds in neonates with gastroschisis, a condition where infants are born with their intestines outside the body.
Eligibility
- Age range
- 0–1 years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Neonates with presumed simple gastroschisis * Born at ≥ 34 weeks' gestation * Hemodynamically stable * Consented within 48 hours after abdominal closure * Mothers who are ≥16 years old * Mothers who speak English or Spanish Exclusion Criteria: * Neonates with evidence of complex gastroschisis at time of closure (any ischemic bowel, intestinal perforation, or obvious atresia with mesenteric defect) * Presence of any major congenital anomalies * Neonates who are receiving ionotropic medications * Neonates who are wards of the state * Neonates whose care is considered to…
Interventions
- ProcedureEarly Feeding Protocol
The intervention includes removal of Replogle within 24 hours of abdominal closure and the initiation of introductory feeds within 48 hours of abdominal closure.
Locations (2)
- University of California Los AngelesLos Angeles, California
- UC Davis Children's HospitalSacramento, California