The Use of Thromboelastography in Burn Injury to Improve Burn Coagulopathy Evaluation and Intervention
Francesco Egro
Summary
This pilot study examines the use of thromboelastography (TEG), a specialized blood test, to evaluate clotting abnormalities in burn patients. The study aims to understand how burn injuries impact the body's ability to form and break down blood clots over time. Specifically, the investigators will research whether the percentage of total body surface area burned (%TBSA) is associated with changes in blood clotting, track the evolution of clotting patterns during the first four weeks following a burn injury, and explore whether these changes can predict recovery or complications. By providing new insights into clotting dynamics in burn patients, the study seeks to improve diagnostic methods, enhance monitoring strategies, and guide treatments to optimize patient care and outcomes.
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Patients admitted with acute burn injuries * Aged 18 years and older * Provided consent to participate in the study Exclusion Criteria: * Patients with a history of venous thromboembolism or hyper/hypocoagulopathy
Interventions
- Diagnostic TestThromboelastography
All participants will receive this intervention. Thromboelastography (TEG) is a blood test that provides a detailed assessment of the clotting process, measuring how blood clots form, strengthen, and dissolve. It offers real-time insights into a patient's coagulation status, helping to identify clotting disorders and guide treatment decisions.
Location
- University of Pittsburgh Medical CenterPittsburgh, Pennsylvania