Comparison Between FL41 Tinted Spectacles, Biomedics55 Premier Contact Lenses, and Altius Tinted Contact Lenses on Photophobia
University of Oklahoma
Summary
Many people suffer from migraine headaches, some more so than others and a common trigger/complaint is light sensitivity, or photophobia1. Some will go to great lengths to avoid light: a dark room with sunglasses on and blankets over the windows, often missing work/school/social activities, etc. Several ocular conditions are accompanied by photophobia, ranging from mild to debilitating.
Description
Burstein et al. describe a shared neuronal pathway between processing light and migraine signals2. Vessels in the dura mater, which are stimulated during migraines, provide input to the Trigeminal Ganglion (TG), which travels to spinal nuclei, which have connections that synapse in the Lateral Posterior Nucleus (LPN). Some intrinsically photosensitive retinal ganglion cells (ipRGC) also synapse through the LPN. The ipRGC are stimulated by light spectra, such as blue light. The crosstalk between the synapses of the ipRGC and pathways from the dura mater vessels causes an overwhelming number of…
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- Yes
Two hundred voluntary subjects will be recruited by researching those who have purchased FL-41 tinted spectacles from the Dean McGee Eye Institute Optical Department. If this does not recruit enough subjects then subject referrals will be solicited from the patient population of the Dean McGee Eye Institute and/or neurology clinics throughout the Oklahoma City metro area. Subjects must meet the following criteria in order to participate in this study: * Subjects must have worn FL-41 tinted spectacles for at least one month prior to participating in this study. * Subjects must have at least 2…
Interventions
- DeviceBiomedics55 Premier contact lenses, and Altius Tinted Contact Lenses
Biomedics55 Premier contact lenses, and Altius Tinted Contact Lenses
Location
- Dean McGee Eye InstituteOklahoma City, Oklahoma