Systems Biology of a mRNA Vaccine Against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Given Via Intradermal (ID) Injection Using Tropis Needle-Free Injection System (NFIS) or Intramuscular (IM) Injection Using Needle and Syringe
PharmaJet, Inc.
Summary
The purpose of this study is to determine if immune responses differ when the mRNA COVID-19 vaccine is given through different delivery methods, including a needle-free injection system, or via intramuscular injection using needle and syringe
Eligibility
- Age range
- 18–50 years
- Sex
- All
- Healthy volunteers
- Yes
Inclusion Criteria: 1. Able to understand and give informed consent 2. Adults aged 18 to 50 years old. 3. Willing and able to comply with all scheduled visits, vaccination, and laboratory tests. 4. Determined by investigator to be in good health based on medical history, targeted physical exam and laboratory testing. 5. Participants with pre-existing stable chronic medical conditions defined as condition not requiring significant change in therapy or hospitalization for worsening disease within 4 weeks from enrollment, can be included at the discretion of the investigator. 6. For women of chi…
Interventions
- BiologicalCOMIRNATY®
COVID-19 Vaccine, mRNA suspension
Location
- Hope Clinic of the Emory Vaccine Center Division of Infectious Diseases, Department of Medicine, School of MedicineDecatur, Georgia