Chronic Loose Stools Following Right-sided Hemicolectomy for Colon Cancer and the Association With Bile Acid Malabsorption and Small Intestinal Bacterial Overgrowth Using a Novel Sampling Device
M.D. Anderson Cancer Center
Summary
The goal of this clinical research study is to learn about gastrointestinal symptoms in participants who have undergone SC or RC and their impact on the quality of life of these participants.
Description
To estimate the microbiota and bile acid profiles at multiple levels of the small intestine and proximal neo-colon in patients after RC and participants after SC.
Eligibility
- Age range
- 20–85 years
- Sex
- All
- Healthy volunteers
- Not specified
Inclusion Criteria: * Both men and women of all races and ethnic groups are eligible for this trial who meet the above criteria. Exclusion Criteria: * Children will not be enrolled in this study. * Pregnant women will not be enrolled in this study. * Cognitively impaired subjects will not be enrolled in this study.
Interventions
- BehavioralCapscan
Participants will be asked to swallow 2 small devices (called Capscan), which will collect samples of intestinal fluid as they move through participants small intestine and colon. This device is not FDA approved but has been deemed to have no significant risk. The investigator can explain how it is designed to work. Participants will also answer surveys about participants quality of life. Participants in this study will be over after all study procedures are completed.
Location
- MD Anderson Cancer CenterHouston, Texas