Visual Perception in Visual Snow Syndrome

Summary

The goal of this study is to learn more about the brain pathways and activity involved in creating Visual Snow Syndrome (VSS). The main questions it aims to answer are: * Does VSS arise from spontaneous activity in brain pathways? * Where in the brain does the activity contributing to VSS arise? * How does brain activity contribute to VSS? Participants will: 1. Undergo assessments and questionnaires to understand visual and mental symptoms, cognitive, and sensory function. 2. Make visual judgements based on images presented to them both inside and outside a magnetic resonance imaging (MRI) machine. 3. Undergo scanning of their brain while inside of an MRI machine.

Eligibility

Age range

18–60 years

Sex

All

Healthy volunteers

Yes

Interventions

• Behavioral
  Visual Adaptation

  Presentation of visual stimuli to quantify the appearance of visual snow or its effects in the visual system of the brain.

• Behavioral
  Assessments and Questionnaires

  Administration of clinical assessments and questionnaires to gather information about visual and mental symptoms, cognitive, and sensory function.

• Device
  Functional Magnetic Resonance Imaging (fMRI)

  7 tesla fMRI data will be acquired during visual paradigms designed to measure neural responses with and without adaptation.

• Device
  Magnetic Resonance Imaging (MRS)

  7 tesla MRS data will be acquired to quantify the concentrations of different brain chemicals in brain regions including visual cortex.

Location