Early Versus Late Endoscopic Temporary Stenting for Management of Refractory Benign Esophageal Strictures
Medical College of Wisconsin
Summary
This project is being done to compare two current treatment clinical options for management of RBES: 1) Frequent dilations followed by temporary esophageal stent placement if dilations fail, or 2) Early stent placement followed by dilations
Description
This study aims to explore the safety and effectiveness of two clinical treatment approaches used to manage RBES patients-Temporary early-stent placement versus late stenting. For normal swallowing, the esophagus (food pipe) lumen should be equal to or more than 14 mm in diameter. In those with stricture (narrowing) of the esophagus from benign causes, initial endoscopic management is serial sessions of dilation (stretching) to achieve and maintain a diameter of ≥14mm. Many strictures may not respond to this approach (refractory). Esophageal stents (18 mm - 23 mm diameter) temporarily placed…
Eligibility
- Age range
- 18+ years
- Sex
- All
- Healthy volunteers
- No
Inclusion Criteria: * Able to give informed and written consent. * Able to keep follow up appointments as per protocol (minimum 2 years). * Biopsy proven benign esophageal stricture. * Dysphagia (grade 2 and above). * Fit to undergo upper GI endoscopy. * Documented esophageal stricture with a luminal diameter \<14 mm at index endoscopy. Exclusion Criteria: * Minimal dysphagia (grade 0-1) * Neuromuscular dysphagia (such as achalasia, oro-pharyngeal dysphagia post-stroke, crico-pharyngeal bar, Zenker diverticulum etc.) * Pregnant or planning to be pregnant during the study period. * Malignant…
Interventions
- DeviceFully covered self-expandable metal esophageal stent
Esophageal stent placement for patients with benign esophageal strictures not responding to endoscopic dilations.
Location
- Froedtert HospitalMilwaukee, Wisconsin