University of Southern California
The objective of this Phase 2 randomized controlled trial is to evaluate the effects of weekly tirzepatide (vs. placebo) on alcohol consumption and cardiometabolic outcomes in adults with alcohol use disorder and overweight or obesity.
Inclusion Criteria: 1. Meeting past-year DSM-5 criteria for AUD with at least moderate severity (≥ 4 symptoms) 2. Average daily consumption of ≥40g (women) / ≥ 60 g (men) per day in the 28 days prior to baseline 3. Body mass index ≥ 27kg/m2 4. Willingness to attend weekly medication visits and complete all study procedures 5. Ability to read and communicate in English 6. Age 21-65 7. Treatment-seeking (i.e., currently seeking assistance to reduce or stop drinking) 8. Stable housing status Exclusion Criteria: 1. Meeting past-year DSM-5 criteria for another substance use disorder (except toba…
Tirzepatide injections (2.5mg, 5.0mg)
Placebo injections
Arctuva estimate
Verify or correct the compensation shown for this listing.